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Heather Powell

  • Associate Professor, Materials Science Engineering
  • Associate Professor, Biomedical Engineering
  • 2041 College Road
    346 MacQuigg Laboratory
    Columbus, OH 43210
  • 614-247-8673

Honors

  • April, 2013

    Lumley Research Award.

  • June, 2012

    Distinguished Undergraduate Research Mentor Award.

  • June, 2012

    Herman Weed Award for Distinguished Teaching.

  • May, 2008

    Ralph E. Powe Junior Faculty Enhancement Award.

  • August, 2004-
    January, 2008

    Shriner's Hospitals for Children Post-Doctoral Research Fellowship.

  • September, 2001-
    September, 2004

    National Defense Science amd Engineering Graduate Fellowship.

  • September, 2000-
    September, 2001

    University Fellow, The Ohio State University.

  • January, 1999-
    June, 1999

    Materials Research Society: Undergraduate Materials Research Initiative Proposal Funded.

  • May, 1999

    National Association of Geoscience Teachers Field Camp Award.

Books

2010

  • Powell, H.M., Lannutti, J.J., Kniss, D.A.. 2010. "Nanoscalar Modifications to Tissue Engineering Polymers: Physical Control of Cell Behavior." VDM Publishing Ltd..

Chapters

2011

  • 2011. "Fluorescein diacetate for determination of cell viability in three-dimensional tissue engineered constructs." In Mammalian Cell Viability, edited by Martin Stoddart,

Journal Articles

2013

  • Willard, J.J., Drexler, J.W., Das, A., Roy, S., Shilo, S., Shoseyov, O.,Powell, H.M., 2013, "Plant-Derived Human Recombinant Collagen Scaffolds for Tissue Engineering." Tissue Engineering Part A 19, no. 13-14, 1507-1518 - 1507-1518.

2012

  • Blackstone, B.N., Powell, H.M., 2012, "Morphogenesis and Biomechanics of Engineered Skin Cultured Under Uniaxial Strain." Advances in Wound Care 1, no. 1/2, 69-74 - 69-74.
  • Blackstone, B.N., Willard, J.J., Nelson, M.T., Hart, R.T., Lannutti, J.J., Powell, H.M., 2012, "Plasma surface modification of electrospun fibers for adhesion-based cancer cell sorting." Integrative Biology 4, no. 9, 1112-1121 - 1112-1121.
  • Blackstone, B.N., Wolever, J.D., and H.M. Powell, 2012, "Structural Alterations in Scaffold Architecture in Response to Mechanical Stimuli." Journal of Tissue Science and Engineering 3, no. 4, 122 - 122.

2010

  • Gundersen, S.I., Chen, G., Powell, H.M., Palmer, A.F., 2010, "Hemoglobin regulates the metabolic and synthetic function of rat insulinoma cells cultured in a hollow fiber bioreactor." Biotechnology and Bioengineering 3, no. 107, 582-592 - 582-592.
  • Ebersole, G.C., Anderson, P.M., Powell, H.M., 2010, "Epidermal Differentiation Governs Engineered Skin Biomechanics." Journal of Biomechanics 16, no. 43, 3183-3190 - 3183-3190.
  • Powell, H.M., K.L. McFarland, D.L. Butler, D.M. Supp and S.T. Boyce, 2010, "Uniaxial strain regulates gene expression, morphogenesis and tissue strength in engineered skin." Tissue Engineering A 16, no. 3, 1083-1092 - 1083-1092.

2006

  • Powell, H.M., Boyce, S.T., 2006, "EDC cross-linking improves skin substitute strength and stability." Biomaterials 27, no. 34, 5821-5827 - 5821-5827.
  • Powell, H.M, Kniss, D.A., Lannutti, J.J., 2006, "Nanotopographic Control of Cytoskeletal Organization." Langmuir 22, no. 11, 5087-5094 - 5087-5094.

2004

  • Wang, H., Lee, J.K., Moursi, A.M., Anderson, D., Winnard, P., Powell, H., Lannutti, J.J., 2004, "Microstructural disassembly of calcium phosphates." Journal of Biomedical Materials Research Part A 68A, no. 1, 61-70 - 61-70.
  • Wang,Haibo; Lee,Jong-Kook; Moursi,Amr,M; Anderson,David; Winnard,Phillip; Powell,Heather; Lannutti,John, 2004, "Microstructural disassembly of calcium phosphates.." Journal of biomedical materials research. Part A 68, no. 1, 61-70 - 61-70.
  • Wang H, Lee JK, Moursi AM, Anderson D, Winnard P, Powell H, Lannutti J, 2004, "Microstructural disassembly of calcium phosphates." Journal of Biomedical Materials Research 68, no. 1, 61-70 - 61-70.

Unknown

  • Fischer, S.N., Weber, M.E., Baran, C.P., Willard, J.J., Johnson, J., Sanders, J.A., Ostrowski, M.C., Lannutti, J.J., Powell, H.M., Ghadiali, S., and C.B. Marsh, "The biostructural and biomechanical effects of eta-2 phosphorylation in pulmonary fibrosis." American Journal of Physiology - Lung Cellular and Molecular Physiology

Presentations

  • "Composite Scaffolds for Improved Engineered Skin Strength and Viability." 2010, Presented at Wound Healing Society and Society for the Advancement of Wound Care Annual Meeting,
  • "Control of Engineered Coaxial Scaffold Strength Using Core Diameter." 2009, Presented at Biomedical Engineering Society Annual Meeting,
  • "Effect of Mechanical Stimulation on Construct Linear Stiffness for MSC-Collagen-Chondroitin-6-Sulfate Tissue Engineered Constructs." 2010, Presented at Midwest Tissue Engineering Consortium,
  • "Culture Under Static Mechanical Load Improves Electrospun Skin Substitute Strength." 2007, Presented at Tissue Engineering and Regenerative Medicine International Society,
  • "Biomaterials as Drug Delivery Devices via Subcritical CO2 Modification." 2004, Presented at Society for Biomaterials World Congress,
  • "Bioengineered Skin Substitutes Fabricated with Electrospun Decrease In Vivo Wound Contraction." 2007, Presented at Tissue Engineering and Regenerative Medicine Society International,
  • "Soft Tissue Biomechanics." 2009, Presented at University of Cincinnati,
  • "PCL-Gelatin Nanofibers for Extended Drug Release." 2011, Presented at MS&T Fall National Meeting,
  • "Somatic Stem Cells for Tissue Engineering." 2009, Presented at Stem Cell Interest Group Meeting,
  • "Mechano-Modulation of Burn Wound Scarring." 2010, Presented at Center for Clinical and Translational Science Pilot Awardee Symposium,
  • "Composite Scaffolds for Skin Engineering." 2010, Presented at Heal Ohio Annual Meeting,
  • "Mechanical and Molecular Strategies to Control Skin Mechanics." 2013, Presented at University of Minnesota, Big Ten BME Invited Lecture Series,
  • "An Experiment-Simulation Approach to Determine Electrospun Fiber Properties." 2011, Presented at MS&T Fall National Meeting,
  • "Influence of Scaffold Hydration on Fiber Geometry and Extension." 2011, Presented at MS&T Fall National Meeting,
  • "A Combined Computational-Experimental Approach to Improving Engineered Skin Biomechanics." 2012, Presented at 5th Annual Translational to Clinical Regenerative Medicine Wound Care Conference,
  • "Materials Development for Biomimetic Engineered Skin Mechanics." 2011, Presented at MS&T Fall National Meeting,
  • "Vascular Wall Engineering via Femtosecond Laser Processing." 2011, Presented at MS&T Fall National Meeting,
  • "Engineered Skin: New Strategies for Biomechanical Mimicry." 2012, Presented at Mathematical Biosciences Institute Workshop on Tissue Engineering,
  • "Effect of Pore Size and Mechanical Stimulation on Stiffness and Col1 Gene Expression of Collagen-C6S Constructs." 2010, Presented at Orthopaedic Research Society Annual Meeting,
  • "Geometric Deformation of Scaffolds as a Function of Scaffold Stiffness." 2011, Presented at TMS Spring Meeting,
  • "Biomaterial, Mechanical and Molecular Strategies to Control Skin Mechanics." 2013, Presented at University of Cincinnati, BME Seminar Series,
  • "Biomaterial, Mechanical and Molecular Strategies to Control Skin Mechanics." 2013, Presented at University of Akron, BME Department Seminar,
  • "Computational Modeling and Scaffold Design in Regenerative Medicine." 2013, Presented at 6th Annual Translational to Clinical Regenerative Medicine Wound Care Conference,
  • "Mechano-Modulation of Burn Wound Scarring." 2013, Presented at BMES Annual Meeting,
  • "Myoferlin Depletion Increases Adhesion and Alters Adhesion Proteins in Breast Cancer Cells." 2013, Presented at BMES Annual Meeting,
  • "Computational Modeling and Mechanical Stimulation for Enhanced Bioengineered Skin Mechanics." 2013, Presented at BMES Annual Meeting,
  • "Engineered Skin Biomechanics: Balancing Biology and Materials Science." 2010, Presented at Department of Mechanical Science Colloquium Series,
  • "Capturing the Local Mechanical Environment and Single Fiber Response in PCL Scaffolds." 2013, Presented at BMES Annual Meeting,
  • "Skin Biomechanics: Role of miRNA and Mechano-Modulation." 2012, Presented at Shriners Hospitals for Children Research Seminar,
  • "Fatigue Properties of Electrospun Tri-Layered Vascular Graft Scaffolds." 2013, Presented at BMES Annual Meeting,
  • "Gene expression and protein production in electrospun skin substitutes cultured under static strain." 2008, Presented at Midwest Tissue Engineering Consortium,
  • "Engineering Biomimetic Skin Mechanics." 2009, Presented at Dorothy M. Davis Heart and Lung Research Institute Research in Progress,

Papers in Proceedings

2009

  • Powell, H.M.; McFarland, K.L.; Butler, D.L.; Supp, D.M. et al. "UNIAXIAL STRAIN REGULATES MORPHOGENESIS, GENE EXPRESSION AND TISSUE STRENGTH IN ENGINEERED SKIN." (1 2009).
  • Powell,Heather,M; McFarland,Kevin,L; Butler,David,L; Supp,Dorothy,M; Boyce,Steven,T "UNIAXIAL STRAIN REGULATES MORPHOGENESIS, GENE EXPRESSION AND TISSUE STRENGTH IN ENGINEERED SKIN." in Wound Healing Society Annual Meeting. (3 2009).
  • Powell,Heather,M; McFarland,Kevin,L; Butler,David,L; Supp,Dorothy,M; Boyce,Steven,T "UNIAXIAL STRAIN REGULATES MORPHOGENESIS, GENE EXPRESSION AND TISSUE STRENGTH IN ENGINEERED SKIN." in Wound Healing Society Annual Meeting. (3 2009).
  • Jain, A.; Kinneberg, K.R.C.; Nirmalanandhan, V.S.; Shearn, J.T. et al. "Regulation of tendon tissue engineered construct stiffness by culture time, mesenchymal stem cells and mechanical stimulation." (12 2009).
  • Powell, H.M.; McFarland, K.L.; Butler, D.L.; Supp, D.M. et al. "UNIAXIAL STRAIN REGULATES MORPHOGENESIS, GENE EXPRESSION AND TISSUE STRENGTH IN ENGINEERED SKIN." (3 2009).
  • Jain,A. Kinneberg,K.R.C., Nirmalanandhan,V.S., Shearn, J.T., Powell, H.M., Gooch, C., Butler,D.L. "Regulation of Tendone Tissue Engineered Construct Stiffness by Culture Time, Mesenchymal Stem Cells and Mechanical Stimulation." in ASME Summer Bioengineering Conference. (1 2009).
  • Jain, A.; Kinneberg, K.R.C.; Nirmalanandhan, V.S.; Shearn, J.T. et al. "REGULATION OF TENDON TISSUE ENGINEERED CONSTRUCT STIFFNESS BY CULTURE TIME, MESENCHYMAL STEM CELLS AND MECHANICAL STIMULATION." in ASME Summer Bioengineering Conference. (1 2009).
  • Jain, A.; Kinneberg, K.R.C.; Nirmalanandhan, V.S.; Shearn, J.T. et al. "REGULATION OF TENDON TISSUE ENGINEERED CONSTRUCT STIFFNESS BY CULTURE TIME, MESENCHYMAL STEM CELLS AND MECHANICAL STIMULATION." (1 2009).

2007

  • Nirmalanandhan, V.S.; Kinneberg, K.R.C.; Juncosa-Melvin, N.; Powell, H.M. et al. "Evaluation of a novel scaffold material for tendon tissue engineering." (12 2007).
  • Kinneberg, K.R.C.; Nirmalanandhan, V.S.; Powell, H.M.; Boyce, S.T. et al. "Combined effect of glycosaminoglycan and mechanical stimulation on the in vitro biomechanics of tissue engineered tendon constructs." (12 2007).
  • Nirmalanandhan, V.S.; Kinneberg, K.R.C.; Juncosa-Melvin, N.; Powell, H.M. et al. "Evaluation of a novel scaffold material for tendon tissue engineering." in ASME Summer Bioengineering Conference. (1 2007).
  • Nirmalanandhan, V.S.; Kinneberg, K.R.C.; Juncosa-Melvin, N.; Powell, H.M. et al. "Evaluation of a novel scaffold material for tendon tissue engineering." (1 2007).
  • Kinneberg, K.R.C.; Nirmalanandhan, V.S.; Powell, H.M.; Boyce, S.T. et al. "Combined effect of glycosaminoglycan and mechanical stimulation on the in vitro biomechanics of tissue engineered tendon constructs." in ASME Summer Bioengineering Conference. (1 2007).
  • Kinneberg, K.R.C.; Nirmalanandhan, V.S.; Powell, H.M.; Boyce, S.T. et al. "Combined effect of glycosaminoglycan and mechanical stimulation on the in vitro biomechanics of tissue engineered tendon constructs." (1 2007).
  • Nirmalanandhan, V.S., Kinneberg, K.R.C., Juncosa-Melvin, N., Powell, H.M., Rao, M., Boyce, S.T., Butler, D.L. "Evaluation of a novel scaffold material for tendon tissue engineering." in Proceeding of the ASME Summer Bioengineering Conference. (1 2007).
  • Nirmalanandhan, V.S., Kinneberg, K.R.C., Juncosa-Melvin, N., Powell, H.M., Rao, M., Boyce, S.T., Butler, D.L. "Evaluation of a novel scaffold material for tendon tissue engineering." in ASME Summer Bioengineering Conference. (1 2007).
  • Kinneberg, K.R.C., Nirmalanandhan,V.S., Powell, H.M., Boyce, S.T., Butler, D.L. "Combined effect of glycosaminoglycan and mechanical stimulation on the in vitro biomechanics of tissue engineered tendon constructs." in ASME Summer Bioengineering Conference. (1 2007).

2004

  • Powell, H.M.; Mitra, S.; Kniss, D.A.; Lannutti, J.J. et al. "Electrospun tubular scaffolds for vascular tissue engineering." (12 2004).

Unknown

  • "Electrospun Tubular Scaffolds for Vascular Tissue Engineering." in Society for Biomaterials World Congress.

Patents

  • Powell, H.M., Sen, C.K., Roy, S.. "VacAid: New Generation Band-Aid for Wound Care."
  • Powell, H.M., Weirich T., Thomson, M.. "Device for Precise Delivery of Heat and Pressure for Burn Wound Generation."
  • Powell, H.M., Lannutti, J.J., Blackstone, B.N.. "Adhesion-Based Cancer Cell Sorting via Electrospun Fiber." Patent number: 61/620,630
  • Powell, H.M., Butler, D.L., Lannutti, J.J., Gilday, S.. "Directed Drug Delivery Scaffold for Improving Tendon-Bone Repair."